Dr Tshepo Motsepe is the spouse of the President of the Republic of South Africa, H.E. Cyril Ramaphosa.
 
Born in Soweto and raised in the rural villages of Mathibestad near Hammanskraal and her ancestral home, Mmakau in the North West province, Dr Motsepe is the eldest of seven siblings and a mother to four children.
 
She is a qualified medical doctor, holding a Bachelor of Medicine and Bachelor of Surgery from the University of KwaZulu-Natal and a Master of Public Health in Maternal Child Health and Aging from the Harvard School of Public Health. She has also completed a Social Entrepreneurship Certificate Programme at the Gordon Institute of Business Science (GIBS).
 
Dr Motsepe has worked in private practice and in hospitals including amongst them, Chris Hani Baragwanath Hospital in South Africa and Parirenyatwa Hospital in Zimbabwe; each the largest in their countries. She also worked with the Wits Reproductive Health and HIV Institute which is a leading African research institute focusing on sexual, reproductive health and HIV research. She has also served as Chairperson of the Gauteng Health Department’s Accreditation Committee.
 
Dr Motsepe is currently the Patron of the Early Care Foundation (previously ASHA Trust), a non-profit organisation which provides early childhood development support programmes for home based crèches in disadvantaged communities. She serves as patron of the South African Civil Society for Women’s, Adolescents’ and Children’s Health (SACSoWACH), the Students Sponsorship Program and a trustee of the Hospice Association of the Witwatersrand. Dr Motsepe is a former member of the National Medical and Dental Association (NAMDA), and the boards of the Vaal Reefs Disaster Trust and the Kids Haven Foundation.
 
In her daily work, Dr Motsepe is guided by the conviction that “economic and social development is a pre-requisite for communities to lead socially and economically productive lives’” as stated in the World Health Organisation’s Alma-Ata Declaration of 1978.